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Sparse solution of nonnegative least squares problems with applications in the construction of probabilistic Boolean networks. (English) Zbl 1349.65140

The authors propose a projection-based gradient descent method for numerical computation of sparse solutions of constrained least squares problems. In each iteration, a projection operator can be also viewed as a soft-thresholding operator where the value of the thresholding is adaptively changing during the iterations. To illustrate the performance of the proposed algorithm, the authors apply the proposed algorithm to solve the inverse problem of constructing a probabilistic Boolean network.

MSC:

65F20 Numerical solutions to overdetermined systems, pseudoinverses
65F10 Iterative numerical methods for linear systems
65F22 Ill-posedness and regularization problems in numerical linear algebra
65C50 Other computational problems in probability (MSC2010)

Software:

Matlab
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References:

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