Cui, Jingan; Ma, Xinchen; Wu, Yucui Meta-population model and vaccination strategy based on population heterogeneity. (Chinese. English summary) Zbl 07801752 Acta Math. Appl. Sin. 46, No. 4, 549-564 (2023). Summary: In this paper, a heterogeneous meta-population SEIAR model is constructed against the background of inoculation of susceptible population, and the basic reproduction number and control reproduction number of the model are calculated by using the next generation matrix method. The effects of preferential mixing mode and heterogeneity on reproduction number are studied. The results show that the heterogeneity of activity, subpopulation size and vaccine coverage have important effects on the number of regenerated cells, and the effects are amplified by preferential mixing. Finally, the optimal control problem with vaccination rate as control variable is studied. The work in this paper can provide reference for the formulation of infectious disease vaccination strategy. MSC: 92C60 Medical epidemiology 35A24 Methods of ordinary differential equations applied to PDEs Keywords:infectious disease dynamics model; heterogeneity; meta-population models; control reproduction number; vaccination × Cite Format Result Cite Review PDF Full Text: Link References: [1] Chow L, Fan M, Feng Z L. Dynamics of a multigroup epidemiological model with group-targeted vaccination strategies. Journal of Theoretical Biology, 2011, 291: 56-64 · Zbl 1397.92626 [2] Levins R. Some Demographic and Genetic Consequences of Environmental Heterogeneity for Biological Control. Bulletin of the Entomological Society of America Oxford Academic., 1969, 15(3): 237-240 [3] Jacquez J A., Simon C P., Koopman J, Sattenspiel L, Perry T. Modeling and analyzing HIV trans-mission: the effect of contact patterns. J. Differential Equations, 2000, 161(2): 307-320 [4] Glasser J, Feng Z L, Andrew Moylan, Sara Del Valle, Carlos Castillo-Chavez. 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