Analyzing repeated measures on generalized linear models via the bootstrap. (English) Zbl 0707.62250

Summary: The analysis of longitudinal data for which the response variables have nonnormal error distributions previously has been complex and/or dependent on restrictive assumptions. In this paper simple methods are introduced for the class of generalized linear models (GLMs). Regressions are fit to the data at each observation time; functions of the resulting coefficients may be bootstrapped, or the coefficients combined through closed-form estimation of their covariances. Application is made to a data set on xerophthalmia in Indonesian children.


62P10 Applications of statistics to biology and medical sciences; meta analysis
62J05 Linear regression; mixed models
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