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Statistical methods in diagnostic medicine. (English) Zbl 1007.62092

Wiley Series in Probability and Statistics. Chichester: Wiley. xvi, 437 p. (2002).
This book provides a comprehensive account of statistical methods for design and analysis of diagnostic studies, including sample size calculations, estimation of the accuracy of a diagnostic test, comparison of accuracies of competing diagnostic tests, and regression analysis of diagnostic accuracy data.
The book has 12 chapters. In the first three chapters, common measures of diagnostic accuracy and various designs for diagnostic accuracy studies are discussed. In Chapters 4 and 5, methods of estimation and hypothesis testing of the accuracies of diagnostic tests are presented. In Chapter 6, sample-size calculations for diagnostic accuracy studies are demonstrated and, in Chapter 7, non-mathematical issues involved in meta-analyses for diagnostic accuracy studies are discussed. In Chapters 8-12, more advanced analytic techniques are discussed, as regression analysis for independent ROC (Receiver Operating Characteristic) data, methods for correcting verification bias, and statistical methods for meta-analysis.
Thoroughly detailed with numerous applications and end-of-chapter problems as well as a related FTP site providing FORTRAN program listings, data sets, and instructional hints, the book is a valuable addition to the literature in the field, serving as a much-needed guide for both clinicians and advanced students.

MSC:

62P10 Applications of statistics to biology and medical sciences; meta analysis
62-02 Research exposition (monographs, survey articles) pertaining to statistics
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