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Estimation of parameters governing the transmission dynamics of schistosomes. (English) Zbl 1063.92028

Summary: The clumping parameter related to the distribution of schistosome parasites is obtained by fitting a negative binomial distribution to data collected from patients in a village in Brazil; the natural uninfected and parasite-induced snail host mortality rates are obtained from laboratory data. These values are used in a schistosomiasis model proposed earlier [Z. Feng et al., Math. Biosci. 177–178, 271–286 (2002; Zbl 0999.92024); J. Math. Biol. 43, 52–68 (2001; Zbl 0986.92017)], and a disease transmission parameter from snails to humans is estimated. Finally, the effect of chemotherapy of humans is assessed using prevalence of morbidity as a measure of the level of schistosome infection in a human population.

MSC:

92C50 Medical applications (general)
62P10 Applications of statistics to biology and medical sciences; meta analysis
92C60 Medical epidemiology
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