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A mathematical model of tumor-immune evasion and siRNA treatment. (English) Zbl 1083.37531
Summary: The authors describe mechanisms by which the cytokines IL-2 and TGF-\(\beta\) mediate the immune response to tumor growth and the added downregulation of this response by tumor cells. In order to study the potential for growth and immune escape of passive and agressive tumors, the authors develop a mathematical model. Moreover, the authors extend the model to include of siRNA treatment.

MSC:
37N25 Dynamical systems in biology
37C45 Dimension theory of smooth dynamical systems
92C99 Physiological, cellular and medical topics
34C60 Qualitative investigation and simulation of ordinary differential equation models
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