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Hemodynamics of cerebral aneurysms. (English) Zbl 1157.76061

Davis, Stephen H. (ed.) et al., Annual review of fluid mechanics. Vol. 41. Palo Alto, CA: Annual Reviews (ISBN 978-0-8243-0741-7/hbk). Annual Review of Fluid Mechanics 41, 91-107 (2009).
Summary: The initiation and progression of cerebral aneurysms are degenerative processes of the arterial wall driven by a complex interaction of biological and hemodynamic factors. Endothelial cells on the artery wall respond physiologically to blood-flow patterns. In normal conditions, these responses are associated with nonpathological tissue remodeling and adaptation. The combination of abnormal blood patterns and genetics predisposition could lead to the pathological formation of aneurysms. Here, we review recent progress on the basic mechanisms of aneurysm formation and evolution, with a focus on the role of hemodynamic patterns.
For the entire collection see [Zbl 1155.76006].

MSC:

76Z05 Physiological flows
76-02 Research exposition (monographs, survey articles) pertaining to fluid mechanics
92C35 Physiological flow
92C10 Biomechanics
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