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An efficient algorithm for deciphering regulatory motifs. (English) Zbl 1269.92035
Feng, Jiafeng (ed.) et al., Networks: from biology to theory. Selected papers based on the presentations at the conference, Sino-German Centre, Beijing, China. London: Springer (ISBN 978-1-84628-485-4/hbk). 249-269 (2007).
Summary: The identification of transcription factor binding sites (TFBS) by computational methods is very important in understanding the gene regulatory network. Although many methods have been developed to identifying TFBSs, they generally have relatively low accuracy, especially when the positions of the TFBS are dependent. Motivated by this challenge, an efficient algorithm, IBSS, is developed for the identification of TFBSs. Our results indicate that IBSS outperforms other approaches with a relatively high accuracy.
For the entire collection see [Zbl 1116.92002].
MSC:
92C40 Biochemistry, molecular biology
92D10 Genetics and epigenetics
92-08 Computational methods for problems pertaining to biology
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