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Conditional inference for restricted randomization designs. (English) Zbl 0651.62019
In a clinical trial to compare two treatments, suppose that patients are assigned to treatment according to a certain class of restricted randomization rules. Conditional on the difference in numbers between the two treatment groups, the asymptotic null distribution of a class of permutation tests is shown to be Gaussian.

MSC:
62E20 Asymptotic distribution theory in statistics
62G10 Nonparametric hypothesis testing
60F05 Central limit and other weak theorems
62P10 Applications of statistics to biology and medical sciences; meta analysis
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