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Modeling of breast cancer through evolutionary game theory. (English) Zbl 1408.92008

Summary: We present a simple mathematical model of the development and progression of breast cancer based on evolutionary game theory. Four types of cellular populations are considered: stromal (native) cells, macrophages, benign tumor cells, and motile (malignant) tumor cells. Despite the relative simplicity of the model, it provides a way to explore the interactions between the various cell types and suggests potential approaches to managing and treating cancer.

MSC:

92C50 Medical applications (general)
91A22 Evolutionary games
91A80 Applications of game theory
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References:

[1] 10.1111/eva.12092
[2] 10.1016/S0959-8049(01)00246-5
[3] 10.1111/j.1365-2184.2008.00563.x
[4] 10.1038/bjc.2011.517
[5] 10.1002/humu.10174
[6] 10.1016/j.ccr.2011.02.006
[7] 10.1086/301749
[8] 10.1189/jlb.1105656
[9] 10.1111/j.1365-2184.2012.00824.x
[10] 10.1016/j.jtbi.2005.05.027 · Zbl 1445.92080
[11] 10.1088/1478-3975/9/6/065007
[12] 10.1186/bcr3143
[13] 10.1371/journal.pone.0006562
[14] 10.1126/science.3798106
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