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Statistical properties of protein-protein interfaces. (English) Zbl 1461.92075

Summary: The properties of 1172 protein complexes (downloaded from the Protein Data Bank (PDB)) have been studied based on the concept of circular variance as a buriedness indicator and the concept of mutual proximity as a parameter-free definition of contact. The propensities of residues to be in the protein, on the surface or form contact, as well as residue pairs to form contact were calculated. In addition, the concept of circular variance has been used to compare the ruggedness and shape of the contact surface with the overall surface.

MSC:

92D20 Protein sequences, DNA sequences
62P10 Applications of statistics to biology and medical sciences; meta analysis

Software:

SCOWLP; COCOMAPS; ProtorP
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References:

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