Castillo-Chavez, Carlos; Feng, Zhilan To treat or not to treat: The case of tuberculosis. (English) Zbl 0895.92024 J. Math. Biol. 35, No. 6, 629-656 (1997). Summary: Incomplete treatment of patients with infectious tuberculosis (TB) may not only lead to relapse but also to the development of antibiotic resistant TB – one of the most serious health problems facing society today. We formulate one-strain and two-strain TB models to determine possible mechanisms that may allow for the survival and spread of naturally resistant strains of TB as well as antibiotic-generated resistant strains of TB. Analysis of our models shows that non-antibiotic co-existence is possible but rare for naturally resistant strains while co-existence is almost the rule for strains that result from the lack of compliance with antibiotic treatment by TB infected individuals. Cited in 1 ReviewCited in 125 Documents MSC: 92C60 Medical epidemiology 37-XX Dynamical systems and ergodic theory 92D30 Epidemiology 34D99 Stability theory for ordinary differential equations Keywords:antibiotic resistance; tuberculosis; co-existence PDFBibTeX XMLCite \textit{C. Castillo-Chavez} and \textit{Z. Feng}, J. Math. Biol. 35, No. 6, 629--656 (1997; Zbl 0895.92024) Full Text: DOI