×

Vascular fluid dynamics and vascular biology and disease. (English) Zbl 1075.76696

Summary: My tribute to James Lighthill, one of the world’s great mathematical scientists, is offered with admiration and sadness - he was both colleague and friend. I met James in 1964, through an introduction by Sir Geoffrey (G.I.) Taylor. He was then Royal Society Research Professor at Imperial College and I was a lecturer in medicine at St. Thomas’s Hospital, with a particular interest in cardiovascular and respiratory mechanics. Within a short while we began to collaborate and about a year later James proposed to Imperial College that it should take the then almost unique step of setting up an activity in physiological flow. The Physiological Flow Studies Unit was started at the College in 1966 - on an experimental basis with a staff of one (the writer). Looking back over a period of more than 30 years, I have three outstanding, interrelated impressions. First, that the field of physiological fluid dynamics has grown hugely worldwide, attesting in no small measure to James Lighthill’s prescience and contributions. Second, that close collaboration between life scientists and doctors and engineers and physical scientists, has led to great advances in the understanding of normal and disturbed biology and of the relevant fluid dynamics. Third, that recognition that mechanical stresses play a key role in cellular and molecular biology, has given a tremendous boost to physiological mechanics. My aim in this note is to describe some earlier and current work on vascular fluid dynamics and vascular biology and disease and, where appropriate, to trace its descent from early studies undertaken with James.

MSC:

76Z05 Physiological flows
92C35 Physiological flow
01A70 Biographies, obituaries, personalia, bibliographies
PDFBibTeX XMLCite
Full Text: DOI

References:

[1] Blood Flow in Arteries. Edward Arnold: London, 1960.
[2] Taylor, Proceedings of the Royal Society A 219 pp 186– (1953)
[3] Caro, Journal of Physiology 183 pp 34– (1966)
[4] Caro, Journal of Physiology l85 pp 50l– (1966)
[5] Lighthill, Journal of the Institute of Mathematical Applications 2 pp 97– (1966)
[6] Caro, Journal of Physiology l94 pp 645– (1967)
[7] Schroter, Respiration Physiology 7 pp 341– (1969)
[8] Responses of the arterial wall to certain physical factors. In Atherogenesis: Initiating Factors, Ciba Foundation, Symposium, vol. l2 (new series), (eds). Associated Scientific Publishers (Elsevier): Amsterdam, London, New York, 1973.
[9] Fry, Circulation Research 22 pp 165– (1968) · doi:10.1161/01.RES.22.2.165
[10] Fry, Circulation Research 24 pp 93– (1969) · doi:10.1161/01.RES.24.1.93
[11] Azarnoff, Proceedings of the Society for Experimental Biology and Medicine 98 pp 680– (1958) · doi:10.3181/00379727-98-24150
[12] Day, Circulation Research 23 pp 779– (1968) · doi:10.1161/01.RES.23.6.779
[13] Caro, Nature 223 pp ll59– (1969)
[14] Caro, Proceedings of the Royal Society B l77 pp l09– (1971)
[15] Transport of material between blood and wall in arteries. In Atherogenesis: Initiating Factors, Ciba Foundation, Symposium l2 (new series) (eds). Associated Scientific Publishers (Elsevier): Amsterdam, London, New York, 1973; 127-164.
[16] Caro, Circulation Research 32 pp l87– (1973) · doi:10.1161/01.RES.32.2.187
[17] Dull, American Journal of Physiology 261 pp h149– (1991)
[18] Dull, Journal of Vascular Research 29 pp 410– (1992)
[19] Levesque, Arteriosclerosis 6 pp 220– (1986) · doi:10.1161/01.ATV.6.2.220
[20] Kamiya, American Journal of Physiology 239 pp 14– (1980)
[21] Langille, Science 231 pp 405– (1986)
[22] Dewey, ASME Journal of Biomechanical Engineering 103 pp 177– (1981)
[23] Levesque, Journal of Biomechanical Engineering 107 pp 341– (1985)
[24] The effect of a fluid-imposed shear stress on the mechanical properties of cultured endothelial cells. In Role of Blood Flow in Atherogenesis. (eds). Springer: Tokyo, 1988.
[25] Nerem, Journal of Biomechanical Engineering 115 pp 510– (1993)
[26] Furchgott, Nature 288 pp 373– (1980)
[27] Davies, Physiological Reviews 75 pp 519– (1995)
[28] Gimbrone, American Journal of Pathology 155 pp 1– (1999) · doi:10.1016/S0002-9440(10)65090-0
[29] Barakat, Circulation Research 85 pp 820– (1999) · doi:10.1161/01.RES.85.9.820
[30] Nollert, Journal of Biomechanical Engineering 114 pp 321– (1992)
[31] Rubanyi, American Journal of Physiology 250 pp h1145– (1986)
[32] Pohl, Journal of Applied Cardiology 1 pp 215– (1986)
[33] Gimbrone, Journal of Clinical Investigation 99 pp 1809– (1997)
[34] Differential gene regulation induced by flow in vascular cells: Implications for gene therapy. Proceedings of the International Conference on New Frontiers in Biomechanical Engineering, Bioengineering Division, JSME, Tokyo, July 18-19, 1997.
[35] Shear stress and nitric oxide release: physiological integration of cellular mechanisms, physical forces and flow regulation. In The Haemodynamic Effects of Nitric Oxide, (eds). Imperial College Press: London, 1999; 22-51. · doi:10.1142/9781848160781_0002
[36] Nagel, Arteriosclerosis Thrombosis and Vascular Biology 19 pp 1825– (1999) · doi:10.1161/01.ATV.19.8.1825
[37] Noria, Circulation Research 85 pp 504– (1999) · doi:10.1161/01.RES.85.6.504
[38] et al. Fluid dynamics of end-to-side vascular grafts. In World Congress of Biomechanics Series, vol. 1: Biological Flows, (eds). Plenum Publishing Corporation: New York, 1995.
[39] Popp, Circulation Research 82 pp 696– (1998) · doi:10.1161/01.RES.82.6.696
[40] Birukov, Circulation Research 81 pp 895– (1997) · doi:10.1161/01.RES.81.6.895
[41] Caro, Atherosclerosis 37 pp 497– (1980)
[42] Caro, Atherosclerosis 46 pp l37– (1983)
[43] Mass transport through the walls of arteries and veins. In World Congress of Biomechanics Series, vol. 1: Biological Flows, (eds). Plenum Publishing Corporation: New York, 1995.
[44] Caro, Journal of Physiology 365 pp 92– (1985)
[45] Naiki, Biorheology 36 pp 225– (1999)
[46] Kjaernes, Acta Pathologica et Microbiologica Scandinavia Section A Pathology 89 pp 35– (1981)
[47] Friedman, Atherosclerosis 39 pp 425– (1981)
[48] Zarins, Circulation Research 53 pp 502– (1983) · doi:10.1161/01.RES.53.4.502
[49] (eds). Fluid Dynamics as a Localising Factor for Atherosclerosis. Springer: Berlin, 1983. · doi:10.1007/978-3-642-69085-3
[50] Role of Blood Flow in Atherogenesis. Springer: Tokyo, 1988. · doi:10.1007/978-4-431-68399-5
[51] (ed). Biofluid mechanics: Proceedings of the 3rd International Symposium VDI-Verlag: Dusseldorf, 1994.
[52] Geometric effects on the hemodynamic environment of the arterial wall: a basis for geometric risk factors? In Fluid Dynamics as a Localising Factor for Atherosclerosis, (eds). Springer: Berlin, 1983; 71-78. · doi:10.1007/978-3-642-69085-3_9
[53] Glagov, Archives of Pathology and Laboratory Medicine 112 pp 1018– (1988)
[54] Ross, New England Journal of Medicine 314 pp 488– (1986)
[55] Ross, New England Journal of Medicine 340 pp 115– (1999)
[56] Ojha, Circulation Research 74 pp 1227– (1994) · doi:10.1161/01.RES.74.6.1227
[57] Tardy, Arteriosclerosis Thrombosis and Vascular Biology 17 pp 3102– (1997) · doi:10.1161/01.ATV.17.11.3102
[58] Spectral and instantaneous flow characteristics of vascular junctions using continuous DPIV. Presented 9th International Symposium on Applications of Laser Techniques to Fluid Mechanics, Lisbon, Portugal, July 13-16, 1998.
[59] Hofer, Journal of Biomechanics 29 pp 1297– (1996)
[60] Non-planar geometry and non-planar-type flow at sites of arterial curvature and branching: implications for arterial biology and disease. In World Congress of Biomechanics Series, vol. 1: Biological Flows, (eds). Plenum Publishing Corporation: New York, 1995.
[61] (ed). Biofluid mechanics: blood flow in large vessels. Proceedings of the 2nd International Symposium. Springer: Berlin, 1990.
[62] (eds). Biomechanical Transport Processes. Plenum Press: New York, 1990. · doi:10.1007/978-1-4757-1511-8
[63] Farthing, Cardiovascular Research 13 pp 607– (1979)
[64] Paulsen, Journal of Biomechanics 16 pp 201– (1983)
[65] Frazin, Circulation 82 pp 1985– (1990) · doi:10.1161/01.CIR.82.6.1985
[66] Yearwood, Journal of Biomechanics 15 pp 683– (1984)
[67] Kilner, Circulation 88 pp 2235– (1993) · doi:10.1161/01.CIR.88.5.2235
[68] Hoydu, Magnetic Resonance Medicine 32 pp 794– (1994)
[69] Batten, Cardiovascular Research 16 pp 178– (1982)
[70] Altobelli, Biomechanical Engineering 107 pp 16– (1985)
[71] Sabbah, Journal of Biomechanical Engineering 106 pp 272– (1984)
[72] Moore, Journal of Applied Physiology 76 pp 1520– (1994)
[73] Back, Journal of Biomechanical Engineering 107 pp 240– (1985)
[74] Atherogenesis in the distal part of the femoral artery: a functional anatomical study of local factors. Ph.D. Thesis, University of Utrecht, 1995.
[75] Perktold, Journal of Biomechanics 21 pp 663– (1988)
[76] Dennis, Quarterly Journal of Mechanics and Applied Mathematics 35 pp 305– (1982)
[77] Berger, Annual Review of Fluid Mechanics 15 pp 461– (1983)
[78] Lou, Critical Reviews in Biomedical Engineering 19 pp 455– (1992)
[79] Asakura, Circulation Research 66 pp 1045– (1990) · doi:10.1161/01.RES.66.4.1045
[80] Karino, Second World Congress of Biomechanics II pp 259a– (1994)
[81] Caro, Proceedings of the Royal Society A 452 pp 185– (1996)
[82] Doorly, ASME FED SM’97 (Bio-Medical Fluids Engineering II) pp 1– (1997)
[83] Sherwin, Journal of Biomechanics 122 pp 1– (2000)
[84] Zabielski, Journal of Fluid Mechanics 370 pp 321– (1998a)
[85] Zabielski, Journal of Fluid Mechanics 370 pp 297– (1998b)
[86] Caro, Journal of Physiology 513P pp 2p– (1998)
[87] Fox, Atherosclerosis 41 pp 337– (1982)
[88] Ding, Arteriosclerosis Thrombosis and Vascular Biology 17 pp 1356– (1997)
[89] The Global Burden of Disease, Global Burden of Disease and Injury Series. Harvard School of Public Health-Harvard University Press: Boston, MA, 1996; 1-34.
[90] Bryan, Current Opinions in Cardiology 9 pp 641– (1994)
[91] Sottiurai, Annals of Vascular Surgery 3 pp 26– (1989)
[92] Bassiouny, Journal of Vascular Surgery 15 pp 708– (1992)
[93] DePaola, Arteriosclerosis, Thrombosis, and Vascular Biology 12 pp 1254– (1992) · doi:10.1161/01.ATV.12.11.1254
[94] Chiu, Circulation Research 85 pp 238– (1999) · doi:10.1161/01.RES.85.3.238
[95] Stonebridge, Journal of Vascular Surgery 26 pp 543– (1997)
[96] Harris, Critical Ischaemia 9 pp 21– (1999)
[97] Geometry and flowfield at arterial bypass grafts: experimental studies. Euromech Colloquium Physiological Flows and Flow-Structure Interactions vol. 389, Graz, April 20-24, 1999; 12pp.
This reference list is based on information provided by the publisher or from digital mathematics libraries. Its items are heuristically matched to zbMATH identifiers and may contain data conversion errors. In some cases that data have been complemented/enhanced by data from zbMATH Open. This attempts to reflect the references listed in the original paper as accurately as possible without claiming completeness or a perfect matching.