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Semiparametric estimation of proportional mean residual life model in presence of censoring. (English) Zbl 1077.62079

Summary: A mean residual life function is the average remaining life of a surviving subject, as it varies with time. The proportional mean residual life model was proposed by D. Oakes and T. Dasu [ibid. 77, No. 2, 409–410 (1990; Zbl 0713.62018)] in regression analysis to study its association with related covariates in absence of censoring. We develop some semiparametric estimation procedures to take censoring into account. The proposed methodology is evaluated via simulation studies, and further applied to a clinical trial of chemotherapy in postoperative radiotherapy of lung cancer patients.

MSC:

62N02 Estimation in survival analysis and censored data
62G05 Nonparametric estimation
62P10 Applications of statistics to biology and medical sciences; meta analysis
62N01 Censored data models

Citations:

Zbl 0713.62018
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