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Multi-state models for event history analysis. (English) Zbl 1121.62568

Summary: An introduction to event history analysis via multi-state models is given. Examples include the two-state model for survival analysis, the competing risks and illness-death models, and models for bone marrow transplantation. Statistical model specification via transition intensities and likelihood inference is introduced. Consequences of observational patterns are discussed, and a real example concerning mortality and bleeding episodes in a liver cirrhosis trial is discussed.

MSC:

62P10 Applications of statistics to biology and medical sciences; meta analysis
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