Metamodeling the learning-hiding competition between tumours and the immune system: A kinematic approach. (English) Zbl 1201.34071

Summary: The competitive interaction between the Immune System and tumours is very complex, being non-linear and, to some extent, evolutionary. A fundamental aspect of this evolution is the asynchronous process of mutual learning of the two populations involved - the tumoural and the immune cells. In this work, to describe them, we propose a simple non-linear family of super-macroscopic models with non-monotonically time-varying coefficients. Numerical simulations of transitory phases complement the theoretical analysis.


34C60 Qualitative investigation and simulation of ordinary differential equation models
92C60 Medical epidemiology
92C50 Medical applications (general)
Full Text: DOI


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