Hopf bifurcation of a mathematical model for growth of tumors with an action of inhibitor and two time delays. (English) Zbl 1218.92049

The authors study a mathematical model for growth of tumors with two discrete delays. The delays, respectively, represent the time taken for cells to undergo mitosis and the time taken for the cell to modify the rate of cell loss due to apoptosis and kill of cells by the inhibitor. The authors study stability of the stationary solutions and, using delays as bifurcation parameter, obtain conditions under which local Hopf bifurcation exist.


92C50 Medical applications (general)
35B32 Bifurcations in context of PDEs
37N25 Dynamical systems in biology
35Q92 PDEs in connection with biology, chemistry and other natural sciences
Full Text: DOI EuDML


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