Stability and sensitive analysis of a model with delay quorum sensing. (English) Zbl 1344.92106

Summary: This paper formulates a delay model characterizing the competition between bacteria and immune system. The center manifold reduction method and the normal form theory due to [T. Faria and L. T. Magalhães, J. Differ. Equations 122, No. 2, 181–200 (1995; Zbl 0836.34068)] are used to compute the normal form of the model, and the stability of two nonhyperbolic equilibria is discussed. Sensitivity analysis suggests that the growth rate of bacteria is the most sensitive parameter of the threshold parameter \(R_0\) and should be targeted in the controlling strategies.


92C60 Medical epidemiology
92D30 Epidemiology


Zbl 0836.34068
Full Text: DOI


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