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TMSmesh

swMATH ID: 14719
Software Authors: Chen M., Lu B.
Description: TMSmesh: A Robust Method for Molecular Surface Mesh Generation Using a Trace Technique. Qualified, stable, and efficient molecular surface meshing appears to be necessitated by recent developments for realistic mathematical modeling and numerical simulation of biomolecules, especially in implicit solvent modeling (e.g., see a review in B. Z. Lu et al. Commun. Comput. Phys. 2008, 3, 973−1009). In this paper, we present a new method: tracing molecular surface for meshing (TMSmesh) the Gaussian surface of biomolecules. The method computes the surface points by solving a nonlinear equation directly, polygonizes by connecting surface points through a trace technique, and finally outputs a triangulated mesh. TMSmesh has a linear complexity with respect to the number of atoms and is shown to be capable of handling molecules consisting of more than one million atoms, which is usually difficult for the existing methods for surface generation used in molecular visualization and geometry analysis. Moreover, the meshes generated by TMSmesh are successfully tested in boundary element solutions of the Poisson−Boltzmann equation, which directly gives rise to a route to simulate electrostatic solvation of large-scale molecular systems. The binary version of TMSmesh and a set of representative PQR benchmark molecules are downloadable at our Web page http://lsec.cc.ac.cn/∼lubz/Meshing.html.
Homepage: http://lsec.cc.ac.cn/~lubz/Meshing.html
Related Software: APBS; MIBPB; tabipb; TetGen; TABI; AFMPB; PHG; PDB2PQR; VCMM; PAFMPB; Apbsmem; CHARMM; ParaView; UHBD; FEtk; SG; FFTSVD; NAMD; MolSurf; nuSMPBIC
Cited in: 22 Documents

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