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ProtIdent

swMATH ID:	16647
Software Authors:	Kuo-Chen Chou, Hong-Bin Shen
Description:	ProtIdent: A web server for identifying proteases and their types by fusing functional domain and sequential evolution information. Proteases are vitally important to life cycles and have become a main target in drug development. According to their action mechanisms, proteases are classified into six types: (1) aspartic, (2) cysteine, (3) glutamic, (4) metallo, (5) serine, and (6) threonine. Given the sequence of an uncharacterized protein, can we identify whether it is a protease or non-protease? If it is, what type does it belong to? To address these problems, a 2-layer predictor, called “ProtIdent”, is developed by fusing the functional domain and sequential evolution information: the first layer is for identifying the query protein as protease or non-protease; if it is a protease, the process will automatically go to the second layer to further identify it among the six types. The overall success rates in both cases by rigorous cross-validation tests were higher than 92
Homepage:	http://www.csbio.sjtu.edu.cn/bioinf/Protease/
Related Software:	Cell-PLoc; Memtype-2L; Signal-CF; GPCR-CA; EzyPred; Euk-mPLoc; Signal-3L; HIVcleave; GPCR-GIA; Euk-PLoc; QuatIdent; Plant-mPLoc; LIBSVM; Virus-ploc; FoldRate; Hum-PLoc; GPCR-2L; iLoc-Euk; iLoc-Hum; iLoc-Virus
Cited in:	21 Publications

all top 5

3	Chou, Kuochen
2	Brahnam, Sheryl
2	Lumini, Alessandra
2	Nanni, Loris
2	Xiao, Xuan
2	Yang, Lianping
2	Zhang, Xiangde
1	Anand, Ashish
1	Anh, Vo V.
1	Araabi, Babak Nadjar
1	Biswas, Neela
1	Dehzangi, Abdollah
1	Deng, Naiyang
1	Ding, Hui
1	Esmaeili, Maryam
1	González Díaz, Humberto
1	Guo, Yanzhi
1	Hoseini, Afsaneh
1	Hoseini, Somayyeh
1	Huang, Dan
1	Huang, Jiangyin
1	Huang, Wei
1	Jahandideh, Mina
1	Jahandideh, Samad
1	Ji, Guoli
1	Jia, Jianhua
1	Jing, Ling
1	Kavousi, Kaveh
1	Li, Jia-Huang
1	Li, Menglong
1	Lin, Hao
1	Liu, Bingxiang
1	Liu, Zi
1	Lyons, James E.
1	Miri Disfani, Fatemeh
1	Mishra, Pooja
1	Mohabatkar, Hassan
1	Mohsenzadeh, Sasan
1	Moosavi-Movahedi, Ali Akbar
1	Moshiri, Behzad
1	Paliwal, Kuldip K.
1	Pandey, Paras Nath
1	Peng, Zhen-Ling
1	Quinn Li, Qingshun
1	Sadeghi, Mehdi
1	Santana, Lourdes
1	Shao, Xiaojian
1	Sharma, Alok
1	Shen, Yingjia
1	Shi, Jianyu
1	Suganthan, Ponnuthurai Nagaratnam
1	Tian, Yingjie
1	Uriarte, Eugenio
1	Vilar, Santiago
1	Wang, Desheng
1	Wang, Jin
1	Wang, Tianming
1	Wang, Yong
1	Wang, Yurong
1	Wu, Lingyun
1	Wu, Xiaohui
1	Wu, Zhicheng
1	Xiao, Rong-quan
1	Yang, Jianyi
1	Yang, Jie
1	Yang, Li
1	Yu, Lezheng
1	Yu, Zuguo
1	Zeng, Yuhong
1	Zhang, Chenyu
1	Zhang, Jianmin
1	Zhang, Ruijie
1	Zhu, Hegui

20	Journal of Theoretical Biology
1	Computational Biology and Chemistry

21	Biology and other natural sciences (92-XX)
8	Statistics (62-XX)
8	Computer science (68-XX)
1	Game theory, economics, finance, and other social and behavioral sciences (91-XX)
1	Information and communication theory, circuits (94-XX)