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PconsFold

swMATH ID: 17011
Software Authors: Mirco Michel, Sikander Hayat, Marcin J. Skwark, Chris Sander, Debora S. Marks, Arne Elofsson
Description: PconsFold: improved contact predictions improve protein models. Motivation: Recently it has been shown that the quality of protein contact prediction from evolutionary information can be improved significantly if direct and indirect information is separated. Given sufficiently large protein families, the contact predictions contain sufficient information to predict the structure of many protein families. However, since the first studies contact prediction methods have improved. Here, we ask how much the final models are improved if improved contact predictions are used. Results: In a small benchmark of 15 proteins, we show that the TM-scores of top-ranked models are improved by on average 33
Homepage: https://github.com/ElofssonLab/pcons-fold
Source Code:  https://github.com/ElofssonLab/pcons-fold
Related Software: Ontobee; PlantTFDB; eggNOG; ELM; dbCAN; antiSMASH; dissectHMMER; HPMV; ANNIE; FreeContact; CCMpred; NNcon; MetaPSICOV; PSICOV; APOLLO; CONFOLD; ncPred; STITCH; MIND-BEST; SPAdes
Cited in: 1 Publication

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