PROSITE swMATH ID: 17326 Software Authors: Sigrist, C.J.A., Cerutti, L., Hulo, N., Gattiker, A., Falquet, L., Pagni, M., Bairoch, A., Bucher, P. Description: PROSITE: a documented database using patterns and profiles as motif. Among the various databases dedicated to the identification of protein families and domains, PROSITE is the first one created and has continuously evolved since. PROSITE currently consists of a large collection of biologically meaningful motifs that are described as patterns or profiles, and linked to documentation briefly describing the protein family or domain they are designed to detect. The close relationship of PROSITE with the SWISS-PROT protein database allows the evaluation of the sensitivity and specificity of the PROSITE motifs and their periodic reviewing. In return, PROSITE is used to help annotate SWISS-PROT entries. The main characteristics and the techniques of family and domain identification used by PROSITE are reviewed in this paper. descriptors Homepage: http://bib.oxfordjournals.org/content/3/3/265.short Related Software: Pfam; BLAST; PSI-BLAST; ClustalW; UniProt; KEGG; MUSCLE; ELM; AAindex; InterProScan; DIALIGN; Phospho.ELM; SMART; R; LIBSVM; ConSeq; Cd-hit; C4.5; RAST; CAP3 Cited in: 19 Documents all top 5 Cited by 44 Authors 2 Appel, Ron D. 2 Gras, Robin 2 Han, Yo-Sub 2 Hernández, David Romero 2 Ko, Sang-Ki 2 Ng, Timothy 2 Salomaa, Kai T. 1 Airola, Antti 1 Amani, Jafar 1 Axelson-Fisk, Marina 1 Basak, Jolly 1 Bologna, Guido 1 Carmel, Amir 1 Chakrabarti, Arunabha 1 Chen, Yen-Kuang 1 Chung, Yun-Sheng 1 Comin, Matteo 1 Deng, Minghua 1 Fattahian, Yaser 1 Gargari, Seyed Latif Mousavi 1 Gonnet, Gaston H. 1 Jiang, Wei 1 Li, Kuo-Bin 1 Li, Tao 1 Lu, Chin Lung 1 Lv, Yingli 1 Marschall, Tobias 1 Ng, Yen Kaow 1 Pahikkala, Tapio 1 Pal, Amita 1 Qian, Minping 1 Rahbar, Mohammad Reza 1 Rasooli, Iraj 1 Romero Navarrete, Lise Rommel 1 Shinohara, Takeshi 1 Tang, Chuan Yi 1 Telles, Guilherme P. 1 Tsur, Dekel 1 Verzotto, Davide 1 Viljanen, Markus 1 Yang, Lei 1 Yu, Huan 1 Ziv-Ukelson, Michal 1 Zuo, Yongchun all top 5 Cited in 12 Serials 4 Theoretical Computer Science 4 Journal of Theoretical Biology 1 Information Processing Letters 1 Algorithmica 1 Information and Computation 1 Machine Learning 1 European Journal of Operational Research 1 Computational Biology and Chemistry 1 Journal of Discrete Algorithms 1 Journal of Applied Logic 1 Computational Biology 1 Algorithms all top 5 Cited in 6 Fields 12 Computer science (68-XX) 11 Biology and other natural sciences (92-XX) 4 Operations research, mathematical programming (90-XX) 1 Combinatorics (05-XX) 1 Probability theory and stochastic processes (60-XX) 1 Statistics (62-XX) Citations by Year