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TM-align

swMATH ID: 22248
Software Authors: Zhang, Y., Skolnick, J.
Description: TM-align: a protein structure alignment algorithm based on TM-score. We have developed TM-align, a new algorithm to identify the best structural alignment between protein pairs that combines the TM-score rotation matrix and Dynamic Programming (DP). The algorithm is ∼4 times faster than CE and 20 times faster than DALI and SAL. On average, the resulting structure alignments have higher accuracy and coverage than those provided by these most often-used methods. TM-align is applied to an all-against-all structure comparison of 10 515 representative protein chains from the Protein Data Bank (PDB) with a sequence identity cutoff <95
Homepage: https://academic.oup.com/nar/article/33/7/2302/2401364
Related Software: BLAST; PSI-BLAST; ClustalW; MAMMOTH; SSAP; Gephi; MEGA; GR-Align; ConSeq; PSLpred; ConFunc; iTOL; PROSITE; Bcepred; Clustal X; MUSCLE; COMPASS; FASTA; SCOPmap; SARSA
Referenced in: 9 Publications

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