iLoc-Hum swMATH ID: 22433 Software Authors: Chou, K. -C.; Wu, Z. -C.; Xiao, X. Description: iLoc-Hum: using the accumulation-label scale to predict subcellular locations of human proteins with both single and multiple sites. Although numerous efforts have been made for predicting the subcellular locations of proteins based on their sequence information, it still remains as a challenging problem, particularly when query proteins may have the multiplex character, i.e., they simultaneously exist, or move between, two or more different subcellular location sites. Most of the existing methods were established on the assumption: a protein has one, and only one, subcellular location. Actually, recent evidence has indicated an increasing number of human proteins having multiple subcellular locations. This kind of multiplex proteins should not be ignored because they may bear some special biological functions worthy of our attention. Based on the accumulation-label scale, a new predictor, called iLoc-Hum, was developed for identifying the subcellular localization of human proteins with both single and multiple location sites. As a demonstration, the jackknife cross-validation was performed with iLoc-Hum on a benchmark dataset of human proteins that covers the following 14 location sites: centrosome, cytoplasm, cytoskeleton, endoplasmic reticulum, endosome, extracellular, Golgi apparatus, lysosome, microsome, mitochondrion, nucleus, peroxisome, plasma membrane, and synapse, where some proteins belong to two, three or four locations but none has 25 Homepage: https://www.ncbi.nlm.nih.gov/pubmed/22134333 Related Software: iLoc-Euk; iLoc-Virus; iRSpot-PseDNC; Cell-PLoc; iLoc-Animal; iAMP-2L; iSNO-PseAAC; iLoc-Gpos; LIBSVM; iLoc-Plant; PseAAC-Builder; propy; Pse-in-One; Plant-mPLoc; iRSpot-TNCPseAAC; Euk-mPLoc; PseAAC; iPro54-PseKNC; PseKNC; Memtype-2L Cited in: 36 Documents all top 5 Cited by 108 Authors 3 Chou, Kuochen 3 Li, Qianzhong 2 Du, Pufeng 2 Fan, Guoliang 2 Hayat, Maqsood 2 Jiao, Ya-Sen 2 Khan, Yaser Daanial 2 Li, Tao 2 Rasool, Nouman 2 Xiao, Xuan 1 Akbar, Shahid 1 Ali, Farman 1 Anh, Vo V. 1 Bakhtiarizadeh, Mohammad Reza 1 Biswas, Neela 1 Butt, Ahmad Hassan 1 Chen, Cheng 1 Chen, Guanyan 1 Chen, Haowen 1 Chen, Wei 1 Cong, Peisheng 1 Dai, Zong 1 Dehzangi, Abdollah 1 Deng, Naiyang 1 Ding, Hui 1 Ding, Zhao-Tang 1 Duan, Xin 1 Ebrahimi, Mansour 1 Ebrahimie, Esmaeil 1 Feng, Peng-Mian 1 Fu, Yi 1 Goliaei, Bahram 1 Guo, Fei 1 Han, Guosheng 1 Hoque, Md Tamjidul 1 Hu, Jianhui 1 Hu, Yinxia 1 Huang, Chao 1 Hussain, Waqar 1 Iqbal, Sumaiya 1 Jahandideh, Samad 1 Jia, Jianhua 1 Jiang, Wei 1 Kaya, Hüseyin 1 Khan, Asifullah 1 Khan, Sher Afzal 1 Kumar, Manish 1 Kumar, Ravindra 1 Kumari, Bandana 1 Kung, Sunyuan 1 Li, Chen 1 Li, Dapeng 1 Li, Tonghua 1 Li, Xiong 1 Li, ZhanChao 1 Liao, Bo 1 Lin, Hao 1 Liu, Bingxiang 1 Liu, Zi 1 Lv, Yingli 1 Lyons, James E. 1 Ma, Qin 1 Madadkar-Sobhani, Armin 1 Mak, Man-Wai 1 Manimegalai, D. 1 Mei, Juan 1 Mei, Suyu 1 Min, Jian-Liang 1 Mishra, Pooja 1 Moradi-Shahrbabak, Mohammad 1 Muthu Krishnan, S. 1 Paliwal, Kuldip K. 1 Pan, Lulu 1 Pandey, Paras Nath 1 Qiu, Wenying 1 Rahimi, Amir Massoud 1 Rahman, Mohammad Sohel 1 Ren, Xianwen 1 Sankari, E. Siva 1 Sharma, Alok 1 Shen, Yinan 1 Srinivasasainagendra, Vinodh 1 Srivastava, Abhishikha 1 Sun, Jiangming 1 Tang, Jijun 1 Tang, Shengnan 1 Tarafder, Sumit 1 Tian, Baoguang 1 Toukir Ahmed, Md. 1 Touserkani, Rouzbeh 1 Wan, Shibiao 1 Wang, Pu 1 Wang, Yongcui 1 Wang, Yu 1 Wu, Xue 1 Xiong, Wenwei 1 Yang, Lei 1 Yu, Bin 1 Yu, Zuguo 1 Yuan, Jingqi ...and 8 more Authors Cited in 2 Serials 35 Journal of Theoretical Biology 1 Computational & Mathematical Methods in Medicine Cited in 5 Fields 36 Biology and other natural sciences (92-XX) 12 Computer science (68-XX) 8 Statistics (62-XX) 1 Harmonic analysis on Euclidean spaces (42-XX) 1 Information and communication theory, circuits (94-XX) Citations by Year