ASPIRE swMATH ID: 32496 Software Authors: princeton Description: Aspire: Algorithms for Single Particle Reconstruction software package. Our project aims to develop mathematical theory, improved algorithms, and open source software for 3-D molecular structure determination using cryo-EM. Our methods use a combination of tools from different areas of mathematics, statistics, and computer science, such as computerized tomography, optimization (convex and non-convex), random matrix theory, signal and image processing, linear and nonlinear dimension reduction, randomized algorithms in numerical linear algebra, and representation theory. Software:The ASPIRE software was originally developed in Matlab. Most of the Matlab code has been ported to Python. Moving forward, the official version is the Python one. Homepage: http://spr.math.princeton.edu Related Software: EMPIAR; Chimera Cited in: 2 Publications all top 5 Cited by 6 Authors 1 Bandeira, Afonso S. 1 Chen, Yutong 1 Lederman, Roy R. 1 Pragier, Gabi 1 Shkolnisky, Yoel 1 Singer, Amit Cited in 1 Serial 2 Inverse Problems all top 5 Cited in 6 Fields 2 Biology and other natural sciences (92-XX) 1 Abstract harmonic analysis (43-XX) 1 Integral transforms, operational calculus (44-XX) 1 Numerical analysis (65-XX) 1 Operations research, mathematical programming (90-XX) 1 Game theory, economics, finance, and other social and behavioral sciences (91-XX) Citations by Year