LncDisease swMATH ID: 34250 Software Authors: Wang, J.; Ma, R.; Ma, W.; Chen, J.; Yang, J.; Xi, Y.; Cui, Q. Description: LncDisease: a sequence based bioinformatics tool for predicting lncRNA-disease associations. LncRNAs represent a large class of noncoding RNA molecules that have important functions and play key roles in a variety of human diseases. There is an urgent need to develop bioinformatics tools as to gain insight into lncRNAs. This study developed a sequence-based bioinformatics method, LncDisease, to predict the lncRNA-disease associations based on the crosstalk between lncRNAs and miRNAs. Using LncDisease, we predicted the lncRNAs associated with breast cancer and hypertension. The breast-cancer-associated lncRNAs were studied in two breast tumor cell lines, MCF-7 and MDA-MB-231. The qRT-PCR results showed that 11 (91.7 Homepage: https://academic.oup.com/nar/article/44/9/e90/2462270 Related Software: starBase; GitHub; DeepWalk; LncADeep; node2vec; ncPred; word2vec; lncRNAdb Cited in: 2 Publications all top 5 Cited by 9 Authors 1 Hui, Zhang 1 Kuang, Linai 1 Siyu, Han 1 Wang, Lei 1 Wei, Du 1 Xuan, Zhanwei 1 Yanchun, Liang 1 Ying, Li 1 Zhao, Haochen Cited in 2 Serials 1 Mathematical Biosciences 1 Computational & Mathematical Methods in Medicine Cited in 2 Fields 2 Biology and other natural sciences (92-XX) 1 Computer science (68-XX) Citations by Year