swMATH ID: 41968
Software Authors: Tao Hu, Yihui Zhou
Description: R package ZIBBSeqDiscovery: Zero-Inflated Beta-Binomial Modeling of Microbiome Count Data. Microbiome count data (Operational Taxonomic Unit, OTUs) is usually overdispersed and has excessive zero counts. The ’ZIBBSeqDiscovery’ assumes a zero-inflated beta-binomial model for the distribution of the count data, and employes link functions to adjust interested covariates. To fit the model, two approaches are proposed (i) a free approach which treats the overdispersion parameters for OTUs as independent, and (ii) a constrained approach which proposes a mean-overdispersion relationship to the count data. This package can be used to test the association between the composition of the microbiome counts and the interested covariates.
Homepage: https://cran.r-project.org/web/packages/ZIBBSeqDiscovery/index.html
Source Code:  https://github.com/cran/ZIBBSeqDiscovery
Dependencies: R
Related Software: R; bzinb; hurdlr; mazeinda; mhurdle; zic; MetaLonDA; ZIBseq; rbtt; iZID; ziphsmm; ZIM; AZIAD
Cited in: 0 Documents