swMATH ID: 
9926

Software Authors: 
Shapiro, B.E., Levchenko, A., Meyerowitz, E.M., Wold, B.J., Mjolsness, E.D.

Description: 
Cellerator: extending a computer algebra system to include biochemical arrows for signal transduction simulations. Summary: Cellerator describes single and multicellular signal transduction networks (STN) with a compact, optionally palettedriven, arrowbased notation to represent biochemical reactions and transcriptional activation. Multicompartment systems are represented as graphs with STNs embedded in each node. Interactions include massaction, enzymatic, allosteric and connectionist models. Reactions are translated into differential equations and can be solved numerically to generate predictive time courses or output as systems of equations that can be read by other programs. Cellerator simulations are fully extensible and portable to any operating system that supports Mathematica, and can be indefinitely nested within larger data structures to produce highly scaleable models. Availability: Cellerator can be licensed free of charge to noncommercial academic, U.S. government, and nonprofit users. Details and sample notebooks are available at http://wwwaig.jpl.nasa.gov/public/mls/cellerator. 
Homepage: 
http://bioinformatics.oxfordjournals.org/content/19/5/677.short

Related Software: 
Mathematica;
BIOCHAM;
STOCHSIM;
Matlab;
Python;
CplexA;
pycellerator;
Dizzy;
BioPEPA;
PRISM;
SICStus;
MGS;
BLOG;
CSPLib;
CMBSlib

Cited in: 
7 Publications
